Welcome to the multidisciplinary research group B3Mat (Biological, Bioinspired and Biomaterials) located in the city of Viña del Mar, Chile.
Our objective is to develop strategies to value the use of natural and artificial biomaterials for potential biotechnological and biomedical applications. For this we have established a multiscale and integrative technological platform of experimental biomechanical models, biological models in vitro and computer models.
At B3Mat we firmly believe that science is a social and collaborative activity, which is why our work not only seeks to carry out high-level research, but also to help it reach citizens.
We are a research group committed to both inclusion and the environment, as well as education and the transfer of scientific knowledge to our community.
BIOLOGICAL, BIOINSPIRED AND BIOMATERIALS
RESEARCH
LAB MEMBERS
The members of our research group come from various branches of science and engineering, forming a multidisciplinary team. In addition, they train undergraduate and postgraduate students, both at the Adolfo Ibáñez University and others nationwide. They also actively collaborate with researchers from Chile and abroad.
FACULTY, FELLOWS AND STAFF
SEBASTIÁN LLANO CÁCERES
MSc in Bioengineering, Universidad Adolfo Ibáñez
-
Specialty: Micromechanical experiments
Thesis : "Characterization and comparison of properties of three-dimensional scaffolds made of thermoplastic polymers with different manufacturing techniques for tissue engineering"
SEBASTIÁN LLANO
MSc in Bioengineering
Lab Manager
JOSÉ CONTRERAS
MSc in Bioengineering
PhD (c) in Complex Systems
JOSÉ CONTRERAS RAGGIO
PhD Student in Complex Systems Engineering, Universidad Adolfo Ibáñez
-
Research Stay at EMPA, Switzerland
-
Field: design & fabrication of scaffolds, macromechanical testing
Project: "Development of bioactive inks for scaffolds 3D printing via direct-ink printing, their mechanical & morphological characterization"
CRISTIAN CALFÚN
PhD in Neurosciences
Part-time Professor
CRISTIAN CALFÚN MEDINA
PhD in Neurosciences, Universidad de Valparaíso, Chile
Part-time Professor, Universidad Adolfo Ibáñez
-
Field: molecular biology, analysis of genetic expression
FERNANDA ÁLAMOS SALCEDO
MSc Student in Bioengineering, Universidad Adolfo Ibáñez
-
Research Stay at EMPA, Switzerland
-
Field: cell culture, molecular biology
Project: "Analysis of osteogenic differentiation of mesenchymal stem cells (MSC) in the interaction with bioglass-based scaffolds for bone tissue engineering"
FERNANDA ÁLAMOS
BSc/MSc Student in Bioengineering
BENJAMÍN RODRÍGUEZ
BSc/MSc Student in Bioengineering
BENJAMIN RODRIGUEZ ROMO
MSc Student in Bioengineering, Universidad Adolfo Ibáñez
Project : "Automatic processing of medical images as a tool to predict damage to musculoskeletal tissues"
RAÚL VALLEJOS BAIER
PhD in Biology, University of Sussex, England.
Academic Instructor, Universidad Adolfo Ibáñez
-
Field: cell culture, scaffold fabrication
RAÚL VALLEJOS
PhD in Biology
Academic Instructor
SIVARAJ DURAIRAJ
PhD in Physics
Postdoctoral Researcher UAI
SIVARAJ DURAIRAJ
PhD in Physics, Bharathidasan University, Tiruchirappalli
Research Associate, Institute of Nano Science and Technology, India
Postdoc, Adolfo Ibáñez University, Chile
Project : "Development of novel M1M2 Substituted Hydroxyapatite/PCL/CNF Composite on TI6AL4V Implant for Orthopedic Application"
MIGUEL BUSTAMANTE S.
Master in Medical Biophysics, University of Chile
PhD (c) in Materials Sciences, University of Chile
MIGUEL BUSTAMANTE
Master in Medical Biophysics. PhD (c) in Materials Science
Luis Perez Pozo
PhD in Mechanical Engineering, Universidad Técnico Federico Santa María (UTFSM)
Assistant Professor, UTFSM
-
Field: finite element analysis (FEA)
LUIS PÉREZ
PhD in Mechanical Engineering
Assistant Professor UTFSM
IRMGARD PARIS
PhD in Biomedical Sciences Professor UST
IMGARD PARIS
PhD in Biomedical Sciences from the Universidad de Chile.
Professor at the Universidad Santo Tomas del Mar
PRINCIPAL INVESTIGATORS
CURRENT STUDENTS
MARIAJESÚS GARRIDO ALONSO
Master's student in Bioengineering, Universidad Adolfo Ibáñez
Project : "Study of scaffold degradation evaluated in a bioreactor system with cell culture medium"
VINCENZO MARCHESE SAAVEDRA
Master's student in Bioengineering, Universidad Adolfo Ibáñez
Project : “Evaluation of the effect on mechanical and biological properties of a structural gradient in scaffolds manufactured by additive manufacturing”
IGNACIO AZOLA ORTIZ
Bioengineering Student, Universidad Adolfo Ibáñez
Project : "Determination of mechanical properties of soft tissue by tensile testing"
JUAN SEBASTIAN CORDOVA CANELO
Bioengineering and Industrial Engineering Student, Universidad Adolfo Ibáñez
Project: "Evaluation of competitiveness of laboratory capabilities for offering a portfolio of services to third parties"
CATALINA ARAYA VALLEJOS
Mechanical Engineering Student, Universidad Técnica Federico Santa María
Thesis : "Experimental characterization of the mechanical properties of different TPMS geometries with functionally directed porosity, application to tissue engineering"
CARLA LOPEZ SILVA
Bioengineering Student, Universidad Adolfo Ibáñez
Project : "Evaluation of cytoskeletal proteins in mesenchymal stem cells (MSC) adhered to biomaterials by fluorescence microscopy"
MÓNICA QUEZADA RIVAS
Bioengineering Student, Universidad Adolfo Ibáñez
Project : “Manufacturing structures with Cellink bioprinter”
FACILITIES
We have equipment at the Bioengineering Center of the Adolfo Ibáñez University (UAI-Bio Center), Viña del Mar Campus. In addition, we have access to equipment outside the University, through collaborations and external services.
MOLECULAR BIOLOGY EQUIPMENT
We have traditional thermal cyclers (Applied Biosystems and Axygen) and a real-time thermal cycler (Agilent AriaMX), a Shimadzu spectrophotometer, a BioTek 800TS plate reader, a Promega Quantus fluorimeter, nucleic acid electrophoresis equipment (CBS Scientific) and proteins ( Biorad), ultracentrifuges (Boeco and Thermofisher) and all the reagents and supplies necessary for enzymatic and molecular analyzes.
CELL CULTURE ROOM
We have a clean room (QClass), which includes all the necessary equipment, such as a BioAir model TopSafe type II biosafety cabinet, a Logos Biosystems model LUNA-II automatic cell counter, a Motic model AE2000 inverted microscope, a ELMI model CM-7S centrifuge, and a Shel Lab model 2406-2 CO2 incubator. In addition, we have stocks of adult stem cells available in nitrogen, along with all the reagents and supplies necessary to perform in vitro experiments.
MECHANICAL EXPERIMENT EQUIPMENT
We have an Electrodynamic system (Test resources 800LE3) to carry out material characterization studies, static resistance and fatigue, with a load level of + -5.7 kN, maximum speed of 125 mm / s, and a maximum frequency of 15 Hz. We also have different types of fixings and load cells for different levels of force. In addition, we have a micromechanical system (Biomomentum model mach-1 v500c) to determine micro-scale mechanical properties.
3D PRINTING
We have commercial fused deposition modeling printers as well as a printer manufactured by our research group, which is used in both research and teaching. We also have 3D bioprinting technology, such as a Cellink Inkredible + biological printer, which has various biotinks to manufacture cell-loaded structures. Finally, we have a wide range of biotinks and polymer filaments and composites that can be used to make samples in the laboratory.